Children in Playground

Children's Postinfectious Autoimmune Encephalopathy Clinic

What is CPAE?

Our Providers

Cheri Standing, MD, FAAP
Sara Reichart, ARNP, CPNP, PPMHS
Sara Rich, BSN, RN, PANS Nurse Navigator
Jessi Ehrsam, BSN, RN

Children's Postinfectious Autoimmune Encephalopathy (CPAE) is a condition where an infection triggers an autoimmune reaction that targets the brain, leading to changes in neurologic function, mood and behavior. PAE includes disorders such as PANS (Pediatric Acute-onset Neuropsychiatric Syndrome), PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infection) and Sydenham chorea.

Does my Child have an Autoimmune Encephalopathy disorder?

Some symptoms of autoimmune encephalopathy (such as PANS/PANDAS):

  • Obsessive Compulsive Disorder (OCD)

  • Restrictive eating

  • Tics

  • Severe anxiety

  • Migraines

  • Irritability and aggression

  • Depression

  • Age regression

  • Sensory sensitivities

  • Hallucinations

Contact Us

CPAE Clinic

Second Floor Medical Arts Plaza

1700 W. Townline St

Creston, IA 50801



8 a.m.- 5 p.m.

What should I do if I think my child has PANS/PANDAS?

If your child’s behavior has suddenly changed within days of being ill and is experiencing new symptoms of OCD or food restrictions along with other neuropsychiatric symptoms, make an appointment with Greater Regional CPAE Clinic to be evaluated.


For a list of available service resources in Union County, Iowa click here.

For a "What is PANS/PANDAS" downloadable pdf, click here.

For a downloadable pdf of "PANS/PANDAS Criteria", click here.

Visit the Greater Regional CPAE Patient page, click here.